Gynecologic Cancer InterGroup (GCIG) consensus review for mullerian adenosarcoma of the female genital tract.
Identifieur interne : 003876 ( Main/Exploration ); précédent : 003875; suivant : 003877Gynecologic Cancer InterGroup (GCIG) consensus review for mullerian adenosarcoma of the female genital tract.
Auteurs : Michael Leonard Friedlander ; Alan Covens ; Rosalind M. Glasspool ; Felix Hilpert ; Gunnar Kristensen ; Sanghoon Kwon ; Frederic Selle ; William Small ; Els Witteveen ; Peter RussellSource :
- International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [ 1525-1438 ] ; 2014.
Descripteurs français
- KwdFr :
- Adénosarcome (), Adénosarcome (anatomopathologie), Association thérapeutique, Consensus, Femelle, Guides de bonnes pratiques cliniques comme sujet, Humains, Oncologie médicale, Sociétés médicales, Tumeurs de l'appareil génital féminin (), Tumeurs de l'appareil génital féminin (anatomopathologie), Tumeurs de l'utérus (), Tumeurs de l'utérus (anatomopathologie).
- MESH :
- anatomopathologie : Adénosarcome, Tumeurs de l'appareil génital féminin, Tumeurs de l'utérus.
- Adénosarcome, Association thérapeutique, Consensus, Femelle, Guides de bonnes pratiques cliniques comme sujet, Humains, Oncologie médicale, Sociétés médicales, Tumeurs de l'appareil génital féminin, Tumeurs de l'utérus.
English descriptors
- KwdEn :
- Adenosarcoma (pathology), Adenosarcoma (therapy), Combined Modality Therapy, Consensus, Female, Genital Neoplasms, Female (pathology), Genital Neoplasms, Female (therapy), Humans, Medical Oncology, Practice Guidelines as Topic, Societies, Medical, Uterine Neoplasms (pathology), Uterine Neoplasms (therapy).
- MESH :
Abstract
Mullerian adenosarcomas of the female genital tract are rare malignancies, originally described in the uterus, the most common site of origin, but they may also arise in extrauterine locations. Uterine adenosarcomas make up 5% of uterine sarcomas and tend to occur in postmenopausal women. They are usually low-grade tumors and are characterized by a benign epithelial component with a malignant mesenchymal component, which is typically a low-grade endometrial stromal sarcoma but can also be a high-grade sarcoma. Tumors that exhibit a high-grade sarcomatous overgrowth have a worse outcome. Adenosarcomas have been described as being midway along the spectrum between benign adenofibromas and carcinosarcomas. They generally have a good prognosis with the exception of deeply invasive tumors or those with high-grade sarcomatous overgrowth. Extrauterine adenosarcomas also have a higher risk for recurrence. In view of their rarity, there have not been any clinical trials in mullerian adenosarcomas and relatively little research. This article reviews the current knowledge and provides recommendation for the management of mullerian adenosarcomas.
DOI: 10.1097/IGC.0000000000000239
PubMed: 25341585
Affiliations:
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Glasspool</name></author><author><name sortKey="Hilpert, Felix" sort="Hilpert, Felix" uniqKey="Hilpert F" first="Felix" last="Hilpert">Felix Hilpert</name></author><author><name sortKey="Kristensen, Gunnar" sort="Kristensen, Gunnar" uniqKey="Kristensen G" first="Gunnar" last="Kristensen">Gunnar Kristensen</name></author><author><name sortKey="Kwon, Sanghoon" sort="Kwon, Sanghoon" uniqKey="Kwon S" first="Sanghoon" last="Kwon">Sanghoon Kwon</name></author><author><name sortKey="Selle, Frederic" sort="Selle, Frederic" uniqKey="Selle F" first="Frederic" last="Selle">Frederic Selle</name></author><author><name sortKey="Small, William" sort="Small, William" uniqKey="Small W" first="William" last="Small">William Small</name></author><author><name sortKey="Witteveen, Els" sort="Witteveen, Els" uniqKey="Witteveen E" first="Els" last="Witteveen">Els Witteveen</name></author><author><name sortKey="Russell, Peter" sort="Russell, Peter" uniqKey="Russell P" first="Peter" last="Russell">Peter Russell</name></author></analytic><series><title level="j">International journal of gynecological cancer : official journal of the International Gynecological Cancer Society</title><idno type="eISSN">1525-1438</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenosarcoma (pathology)</term><term>Adenosarcoma (therapy)</term><term>Combined Modality Therapy</term><term>Consensus</term><term>Female</term><term>Genital Neoplasms, Female (pathology)</term><term>Genital Neoplasms, Female (therapy)</term><term>Humans</term><term>Medical Oncology</term><term>Practice Guidelines as Topic</term><term>Societies, Medical</term><term>Uterine Neoplasms (pathology)</term><term>Uterine Neoplasms (therapy)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adénosarcome ()</term><term>Adénosarcome (anatomopathologie)</term><term>Association thérapeutique</term><term>Consensus</term><term>Femelle</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Oncologie médicale</term><term>Sociétés médicales</term><term>Tumeurs de l'appareil génital féminin ()</term><term>Tumeurs de l'appareil génital féminin (anatomopathologie)</term><term>Tumeurs de l'utérus ()</term><term>Tumeurs de l'utérus (anatomopathologie)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Adénosarcome</term><term>Tumeurs de l'appareil génital féminin</term><term>Tumeurs de l'utérus</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Adenosarcoma</term><term>Genital Neoplasms, Female</term><term>Uterine Neoplasms</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Adenosarcoma</term><term>Genital Neoplasms, Female</term><term>Uterine Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Combined Modality Therapy</term><term>Consensus</term><term>Female</term><term>Humans</term><term>Medical Oncology</term><term>Practice Guidelines as Topic</term><term>Societies, Medical</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adénosarcome</term><term>Association thérapeutique</term><term>Consensus</term><term>Femelle</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Oncologie médicale</term><term>Sociétés médicales</term><term>Tumeurs de l'appareil génital féminin</term><term>Tumeurs de l'utérus</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Mullerian adenosarcomas of the female genital tract are rare malignancies, originally described in the uterus, the most common site of origin, but they may also arise in extrauterine locations. Uterine adenosarcomas make up 5% of uterine sarcomas and tend to occur in postmenopausal women. They are usually low-grade tumors and are characterized by a benign epithelial component with a malignant mesenchymal component, which is typically a low-grade endometrial stromal sarcoma but can also be a high-grade sarcoma. Tumors that exhibit a high-grade sarcomatous overgrowth have a worse outcome. Adenosarcomas have been described as being midway along the spectrum between benign adenofibromas and carcinosarcomas. They generally have a good prognosis with the exception of deeply invasive tumors or those with high-grade sarcomatous overgrowth. Extrauterine adenosarcomas also have a higher risk for recurrence. In view of their rarity, there have not been any clinical trials in mullerian adenosarcomas and relatively little research. This article reviews the current knowledge and provides recommendation for the management of mullerian adenosarcomas.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Covens, Alan" sort="Covens, Alan" uniqKey="Covens A" first="Alan" last="Covens">Alan Covens</name><name sortKey="Friedlander, Michael Leonard" sort="Friedlander, Michael Leonard" uniqKey="Friedlander M" first="Michael Leonard" last="Friedlander">Michael Leonard Friedlander</name><name sortKey="Glasspool, Rosalind M" sort="Glasspool, Rosalind M" uniqKey="Glasspool R" first="Rosalind M" last="Glasspool">Rosalind M. Glasspool</name><name sortKey="Hilpert, Felix" sort="Hilpert, Felix" uniqKey="Hilpert F" first="Felix" last="Hilpert">Felix Hilpert</name><name sortKey="Kristensen, Gunnar" sort="Kristensen, Gunnar" uniqKey="Kristensen G" first="Gunnar" last="Kristensen">Gunnar Kristensen</name><name sortKey="Kwon, Sanghoon" sort="Kwon, Sanghoon" uniqKey="Kwon S" first="Sanghoon" last="Kwon">Sanghoon Kwon</name><name sortKey="Russell, Peter" sort="Russell, Peter" uniqKey="Russell P" first="Peter" last="Russell">Peter Russell</name><name sortKey="Selle, Frederic" sort="Selle, Frederic" uniqKey="Selle F" first="Frederic" last="Selle">Frederic Selle</name><name sortKey="Small, William" sort="Small, William" uniqKey="Small W" first="William" last="Small">William Small</name><name sortKey="Witteveen, Els" sort="Witteveen, Els" uniqKey="Witteveen E" first="Els" last="Witteveen">Els Witteveen</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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